Fractional Chief of Staff to Biotech CEOs and Boards
Former VP, Programs & Portfolio | Biotech Execution & Capital Discipline
Bringing clarity, alignment and accountability at critical inflection points.
When portfolio complexity meets capital pressure, clarity becomes strategic.
Biotech organizations operate under structural tension:
milestone dependencies, regulatory uncertainty, capital constraints and increasing Board scrutiny.
As pipelines expand and expectations rise, execution discipline and governance clarity become decisive differentiators.
This is where a Fractional Chief of Staff becomes a strategic lever.
What I bring
Fractional Chief of Staff to Biotech CEOs and Boards.
I step in at moments of strategic inflection —
when portfolio complexity increases, capital pressure intensifies and execution credibility becomes critical.
I bring clarity, alignment and accountability
without adding unnecessary structure.
Core Areas
Executive and Board interface structuring
Strategic prioritization under capital constraints
Cross-functional leadership alignment
Governance discipline and milestone accountability
Embedded fractional Chief of Staff leadership
Executive Experience in High-Stakes Biotech Environments
Carole ABEL
Founder - enAbel Consulting
Three decades of professional experience, with over 20 years dedicated to biotech and pharmaceutical development in complex, capital-sensitive environments.
Former Vice President, Programs & Portfolio Office at MindMed.
Leadership roles at Actelion Pharmaceuticals and Creso Pharma.
Operated in close proximity to executive teams and Boards where capital allocation, portfolio focus and execution credibility directly impact valuation.
Today, I operate as a Fractional Chief of Staff, bringing this experience directly into biotech leadership teams.
Typical Situations I Support
Rapid pipeline expansion with constrained organizational capacity
Board pressure on prioritization and milestone credibility
CEO and ExCom bandwidth overload during scale-up
Governance complexity following financing rounds
Capital allocation trade-offs across development programs
Cross-functional misalignment slowing execution
Leadership bandwidth overload
When governance discipline and execution credibility are under pressure, it is the right moment to intervene.
Engagement Models
Fractional Chief of Staff (Embedded Executive Partner)
1–3 days per week, aligned to strategic milestones and leadership priorities.
Board & Portfolio Governance Advisory
Targeted strategic decision support at CEO and Board level.
Conseil auprès de dirigeants de TPE/PME (France)
J’accompagne également les dirigeants de TPE/PME dans la structuration de leur gouvernance, la priorisation des enjeux et la prise de décisions stratégiques lors des phases de croissance ou de transformation.
Let’s Talk.
If portfolio complexity, capital discipline or execution credibility are becoming strategic concerns, it may be the right time to introduce a Fractional Chief of Staff.
Confidential. Direct. Executive-level engagement.